Although I like the idea of changing the Doctor’s gender, I’d say that adt1957 has a point, in that I’d say a lot of fans would have an issue with it. I would think that there’d be a lot of opposition as people are so used to the Doctor being a man. If they were to change the Doctor to a woman they’d have to be very careful about who they chose, because if the individual turned out to not be very good, then people who opposed the change in the first place would become even more opposed to the alteration in gender. Also, as a matter of interest, has the Doctor ever been talked about being with a man?